However, these preclinical findings do not establish safety for use during human pregnancy, as species differences in placental transfer and fetal metabolism may exist
Garg A, Sharma A, Krishnamoorthy P, et al
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Restoring NAD+ levels in aging and metabolic stress models improved glucose tolerance, mitochondrial function, and overall health [1]
They argue its safety concerns are ill-defined and that regulators are too focused on efficacy for products that are intended for use only on a case-by-case basis