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*As indicated in preclinical and medical research contexts

Yet, plasma concentrations of vitamin C 50 mol/L are sufficient to saturate muscle tissue vitamin C

When they occur, its usually when doses are increased, then tend to improve once a steady dose is reached

Galvano, F., Li, Volti G., Malaguarnera, M., Avitabile, T., Antic, T., Vacante, M., and Malaguarnera, M