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Accordingly, several in vitro studies aimed at assessing the efficacy of drugs on glucose-related cell damage in ARPE-19 reported that using euglycemic media (5.5 mM) as a control condition may affect normal cell growth [48]
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Like other nonsteroidal anti-inflammatory drugs, ibuprofen inhibits platelet aggregation, but, because of its low effectiveness and reversibility, it is not used to treat this condition [11]
Interestingly, NPY, the hunger neuropeptide responsible for ensuring food intake and reducing anxiety and stress was significantly reduced by 21% after MPH intake and non-significantly increased by 11% in the Pycnogenol group
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