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10.1016/j.redox.2021.102041 Redox Biol
Lipsitz, Ponterio & Comerford has spent decades doing exactly that
and it has demonstrated analgesic properties in animal studies
Apart from the local adverse effects of these agents, the important limitation is the localization of their effect to the site of application alone
Unlike many conventional treatments, its mechanism of action focuses directly on appetite regulation rather than simply increasing energy expenditure
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