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No dose-ranging studies have established safety margins, optimal administration routes, or duration of treatment
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Modulation of VEGFR2 and eNOS pathways by BPC-157. PubMed Source: Journal of Physiology Angiogenic and vascular effects in ischemia models
Zeng L et al
This is based on the role of SAM as both an allosteric activator of cystathionine -synthase and an allosteric inhibitor of MTHFR, the enzyme that produces 5-methyltetrahydrofolate (Figure 2)
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