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Acronyms A1C - Hemoglobin A1C ADA - American Diabetes Association AHA - American Heart Association AUD - Alcohol use disorder CAD - Coronary artery disease CrCl - Creatinine clearance CVD - Cardiovascular disease DM - Diabetes mellitus FBS - Fasting blood sugar GFR - Glomerular filtration rate GI - Gastrointestinal GLP-1 - Glucagon-like peptide-1 HFpEF - Heart failure with preserved ejection fraction MASH - Metabolic dysfunctionassociated steatohepatitis NAION - Nonarteritic anterior ischemic optic neuropathy OSA - Obstructive sleep apnea PAD - Peripheral artery disease RCT - Randomized controlled trial SBP - Systolic blood pressure Thyroid C-cell tumor = Thyroid medullary tumor WOMAC - Western Ontario and McMaster Universities Osteoarthritis Index DRUGS IN CLASS GLP-1 analogs Semaglutide (Wegovy) is a GLP-1 analog, a drug class originally developed to treat type 2 diabetes

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FDA) Real-world titration, persistence & weight loss of semaglutide and tirzepatide (PMC, NIH)

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Some patients experienced changes in their thyroid nodules, while others did not