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This family of compounds represents a new class of drugs with lead candidates that are orally active, penetrate the BBB sufficiently to reach therapeutic concentrations, and reverse memory deficits seen in animal models of dementia

Rasch model A mathematical framework against which test developers can compare empirical data to assess an instruments capacity to emulate the properties of fundamental measurement (invariance and unidimensionality) and thus serve as a tool for quantifying unobservable human conditions

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2) Dihexa was shown to improve cognitive impairments and recover memory by inhibiting inflammation and decreasing neuronal loss by affecting the PI3K/AKT signaling pathways