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Dubey S, Misra P, Dwivedi S et al (2010) Transcriptomic and metabolomic shifts in rice roots in response to Cr (VI) stress

These metabolites can simultaneously drive inflammatory processes, such as oxidative stress or excitotoxicity, while activating compensatory anti-inflammatory mechanisms like IL-10 production, reflecting their inherently bidirectional immunomodulatory roles in the brain

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Conservative doses may fall below effective threshold for some individuals