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ERK1/2 & VEGFR2 Mechanism Musculoskeletal Scoping Review (PMC, 2025) A 2025 scoping review confirmed BPC-157 activates VEGFR2 and drives nitric oxide synthesis via the Akt-eNOS axis, promoting angiogenesis, fibroblast activity, and neuromuscular stabilisation

For Clinicians: Maintain evidence-based practice, avoid hype

CMS proposed expanding Part D to include anti-obesity medications for 2026, but the government decided against it, which means the OSA indication remains the only Medicare pathway for Zepbound

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