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It is worth noting that although these are the common dosages and frequencies for B12 injections, that does not mean that they are set in stone
Genetics of intracellular vitamin B12 metabolism
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Titration: There is generally no need for upward titration with B-complex vitamins as one might do with certain drugs, but if a patient is frail or known to react to injections, the provider may choose to start at a lower dose (for example 0.25-0.5 mL) and then increase to 1 mL as tolerated
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