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Astaxanthin One of the most powerful natural antioxidants Protects cells from oxidative damage Supports skin, eye, and cardiovascular health 5

This inflammatory synovial fibroblast phenotype exacerbates cartilage degeneration, via the induction of matrix metalloproteases (MMPs) and aggrecanases (ADAMTS4/5), and sensitises the growth and activity of joint nociceptors [92,93,94]

For example, GSH non-enzymatic can reduce glutaredoxin-2 (GLRX2) and TXNRD can also reduce it with no enough GSH

The formation of dual-species biofilm also shows a high degree of resistance to combined antifungal and antibacterial treatment [195,196,197,198]