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In vitro N -glucuronidation of a novel antiepileptic drug, lamotrigine, by human liver microsomes

The following gRNA target sequences were employed to generate ARL8 DKO cell line: sgRNA for ARL8A : CGCGATCACGTTGACGAAGG, and sgRNA for ARL8B : AGAGATGGAGCTGACGCTCG 20

Sirt5 plays a critical role in mitochondrial protein acylation and mitochondrial metabolic homeostasis in brown fat