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doi: 10.1210/en.2014-2001 290 TanBKHallschmidMAdyaRKernWLehnertHRandevaHS
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The cellular necrosis after an APAP overdose leads to release of cell contents, which includes molecules termed damage-associated molecular patterns (DAMPs) that can bind to pattern recognition receptors, e.g., toll like receptors, on macrophages and trigger formation of various cytokines and chemokines [8690]
While the whitening effect may still spark debates, there is no denying the powerful antioxidant properties and detoxification support it provides
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