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TB-500 operates primarily through actin dynamics: it binds G-actin monomers to regulate the monomeric actin pool, which is thought to influence cell migration in experimental wound models

This makes it one of the richest dietary sources of this compound, which rarely occurs in high amounts in food

The peptide binds copper(II) with high affinity and facilitates its transfer to relevant metalloenzymes and cellular systems

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, 8 found lower activities of CuZn-SOD, GPx and CAT in the renal medulla, lower levels of CuZn-SOD, GPx but higher activity of CAT in the renal cortex, whereas Mn-SOD activity was increased in both the cortex and medulla of stroke-prone SHR when compared with age-matched 32-week-old WKY rats