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HFD inhibits the transcription of key antioxidant genes by triggering NRF2 translocation into obese mouse Tregs nucleus, causing a rapid decline in HO-1 expression in Tregs, leading to enhanced oxidative stress and possible ferroptosis, and causing an intensification of obesity and inflammatory responses (156) ( Figure 3 )

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Managing Weight Fluctuations During the Transition to Menopause Weight Loss and Metabolic Health Weight gain during the perimenopausal transition is a common concern for many women, often exacerbated by hormonal changes that affect metabolism and body composition

Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation

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