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Reactive oxygen disrupts mitochondria in MA-10 tumor Leydig cells and inhibits steroidogenic acute regulatory (StAR) protein and steroidogenesis

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In an animal experiment, GLP-1 and exendin-4 (a GLP-1 mimetic) reversed the decrease in bone mass of femurs and vertebrae in hyperlipidic and hypercaloric Wistar rats ( n = 36) or insulin glargine ( n = 33)

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