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The most common side effects, such as nausea, tend to diminish over time as your body adjusts to the medication

While initially developed for managing type 2 diabetes, these medications have proven effective for weight loss therapy, offering additional benefits such as improved blood sugar control and better cardiovascular health

In June 2024, tirzepatide (Zepbound, Mounjaro) was added to the FAAs Acceptable Weight Loss Medications category, clearing the path to general eligibility medical certification for pilots and ATCS

Despite an emerging consensus that these peripherally administered GLP1RAs exert their effects on appetite suppression through the central nervous system, knowledge of the neural pathways and intracellular signaling mechanisms by which they act in the brain remains limited

Beyond weight loss, semaglutide enhances general health, addressing factors like heart disease, stroke, and type 2 diabetes