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Hepatic impairment (OFV = 1.281), water volume 50 mL vs 120 mL (OFV = 3.328), age 65 years (OFV = 3.024), sex (OFV = 0.102) and renal impairment (OFV = 2.099) were excluded in the final model (in that order)
Although GLP-1s are generally safe for the liver, its important to check, especially before compounded meds Kidney function: to watch for stress on the kidneys, which can be exacerbated by GLP-1-induced dehydration and nausea, especially in older adults or those with preexisting conditions [1] Thyroid markers : to screen for an under-functioning thyroid gland, which can mimic or worsen weight gain
I started with a 0.25 mg dose and will move to the 0.5 mg dose after the 4th week
These medications are generally considered safe to use alongside SSRIs when taken at recommended doses, and they are often the preferred choice for people managing allergies whilst on antidepressant therapy
With age, nighttime melatonin often drops, disrupting the natural sleep-wake cycle and indicating a less active pineal gland
