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Symptoms include gas, bloating, abdominal pain, cramping, and diarrhea or constipation
Improvements in blood pressure, lipids, and blood sugar control followed the same pattern
[1] TML is then hydroxylated into hydroxytrimethyllysine (HTML) by trimethyllysine dioxygenase (TMLD), requiring the presence of ascorbic acid and iron
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The FLOW study highlights the risks of CKD progression, cardiovascular disease and death in those with type 2 diabetes and CKD, and the significant benefits of the pillars of treatment: ACE inhibitors/ARBs, SGLT2 inhibitors, finerenone and, now, semaglutide
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