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Cecal ligation and puncture (CLP) sepsis model Two different procedures were used (mild or severe) when the mice were sacrificed after 24 h (mild model) and when a survival experiment was performed (severe model)

The results revealed that the levels of pro-inflammatory cytokines IL-6, IL-12, and TNF- secreted by cells treated with NP4 were 1.45, 5, and 1.78 times higher than those secreted by cells treated with NP2, respectively, further confirming the activation of macrophages

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Anim Models Exp Med

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