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In MS patients, administering a mixture of probiotics (enriched with Lactobacillus, Streptococcus , and Bifidobacterium ) switched the peripheral immune response to an anti-inflammatory one and reversed the microbiota composition changes associated with MS (Lavasani et al., 2010)

NH 2 OH was removed by methanol-chloroform-water precipitation and the protein pellets resuspended in TEA buffer with 0.2% Triton X-100 were incubated with 1 mM of mPEG-Mal (5 kDa) for 2 h at room temperature

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This fundamental difference in their mechanisms contributes to their varying efficacy in different therapeutic applications