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Preclinical evidence suggests that acetyl-l-carnitine is endowed with antidepressive properties related to the epigenetic regulation of mGlu2 expression [32]
Preclinical studies have found that berberine increases the number of tyrosine hydroxylase (TH)-positive neurons in the substantia nigra, at the same time, berberine also increases striatum dopamine, norepinephrine, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid levels (Shin et al., 2013)
J Chromatogr B
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