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Diarrhoea is an uncommon side effect of vitamin B12 supplementation, listed as a rare adverse reaction in UK product information for both oral and injectable preparations

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This makes weight loss more difficult, even with diet and exercise

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5-Amino-1MQ reduces NNMT, improving fat function, inflammation, mitochondrial output, and muscle repair.[23][32] In adipocytes, it boosts NAD+ by preventing its wasteful methylation, leading to better glucose handling