why does tirzepatide cause heartburn Mounjaro & Heartburn: GLP-1 Digestive Effects Explained The Definitive Guide to Tirzepatide

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Orforglipron, an oral small-molecule GLP-1 receptor agonist, for the treatment of obesity in people with type 2 diabetes (ATTAIN-2), The Lancet, 2025

Downregulating the expression of miR-23a and increasing the expression of the mitochondrial protective gene peroxisome proliferators-activated receptor- coactivator-1 (PGC-1) can exert an anti-apoptotic effect on human hepatocytes [34]

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GLP-1 receptor agonists work by mimicking the bodys natural GLP-1 hormone, which regulates appetite and food intake by targeting specific receptors in the brain, according to Willow, an online company that sells GLP-1s