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Subsequently, the authors determined general radiosensitivity ( D 0 dose reducing surviving fraction to 37%), quasi-threshold doses ( D q ), and extrapolation numbers ( n ) from the survival curves and correlated these parameters with the cellular levels of GPx, catalase, CuZn superoxide dismutase (Cu/Zn-SOD), and Mn superoxide dismutase (Mn-SOD)

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One patient receiving VK2735 experienced a serious adverse event (SAE) of dehydration that was characterized as related to study drug

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