How GLP-1-Based Medications Work GLP-1-based therapies - including compounded versions - work by enhancing the bodys natural appetite and glucose regulation processes: Appetite Signaling: Helps you feel full with less food Insulin Modulation: Encourages insulin release to manage post-meal blood sugar Gastric Delay: Slows stomach emptying, which can support smaller portion sizes These effects make GLP-1 medications a promising option for those looking to support long-term health with provider guidance
What Happens with Chronic Stress: Cortisol dysregulation can lead to immune imbalance and rebound inflammation Skin barrier function decreases , leading to dryness, irritation, and flares Hormone levels like estrogen, progesterone, and thyroid can become disrupted Cortisol resistance may develop, where tissues no longer respond effectivelyresulting in inflammation thats harder to control In women, stress also affects menstrual cycles, which can worsen hormone-related eczema
While the nephroprotective effects of SGLT2i were initially derived from secondary endpoints of CV outcome trials (CVOTs), direct confirmation came from dedicated kidney focused trials: CREDENCE (Perkovic et al NEJM 2019| NephJC Summary), DAPA-CKD (Heerspink et al NEJM 2020| NephJC Summary) and finally EMPAKIDNEY (Herrington et al NEJM 2023| NephJC Summary)
When injecting it into the BPC-157 vial, aim the stream against the side of the glass vial, not directly onto the peptide powder
Disclosure: This research was supported by Novo Nordisk