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In fact, because the RFC pathway is less efficient, studies use high doses of leucovorin to ensure enough folate reaches the brain

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It seems simple, but a misplaced decimal point in your calculation can throw off your entire dosing protocol

Symptoms may include: Shortness of breath Red, flushed skin Headaches Rapid weight gain, polycythemia (increased red cell mass), hypokalemia, CHF, pulmonary edema, and vascular thrombosis are mostly observed in therapeutic contexts where vitamin B12 is administered aggressively or over extended periods

Stale COAs may not reflect current batches