Serious side effects are rare, but contact a doctor immediately for severe tummy pain, persistent vomiting, allergic reactions, or worrying mood changes
In comparison, 7,293 individuals (8.0%) with an estimated HbA1c advantage on GLP1-RA showed a 16 mmol/mol drop in HbA1c, whereas SGLT2i recipients had a nine mmol/mol decrease in HbA1c
This might mean stepping back from 15 mg to 10 mg, or from 10 mg to 7.5 mg
11 We now have a therapy that was tested in a very modest size clinical trial, with STEP-HFpEF having just over 500 patients, but really produced the largest, to my knowledge, quality of life improvement that we've ever seen in a heart failure trial, Stephen Greene, MD, a heart failure cardiologist with Duke University Medical Center, said in an interview with HCPLive
Always consult a healthcare professional before combining these drugs with other treatments