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The tirzepatide results guide contextualizes what these different doses mean for outcomes

The GIP receptor activation in tirzepatide appears to moderate the gastrointestinal effects of GLP-1 receptor activation

Most of the studies used once weekly subcutaneous injection of semaglutide starting at a dose of 0.25 mg and escalated every 4 weeks

Repeatedly dosing early (creating a pattern of 5- to 6-day intervals) effectively increases your dose and may increase side effects without improving weight loss

*Correspondence: Ping Wang, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers