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17 , 903912, e944-9 (2010)

Esculetin, a coumarin derivative, exhibits anti-proliferative and pro-apoptotic activity in G361 human malignant melanoma

The free energy of a typical reaction is calculated directly from its E o by the Nernst equation as shown below, where n is the number of electrons involved in the reaction and F is the Faraday constant (23.06 kcal/volt/mol or 94.4 kJ/volt/mol): G = nF E o For the oxidation of NADH, the standard biological reduction potential is 52.6 kcal/mole