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This complex interplay within the Nrf2/HO-1 pathway remains under active investigation, as it represents a double-edged sword that can be either protective or harmful depending on the precise balance of iron and ROS levels within the cell (37)

longum BB 536 demonstrated to modulate the expression of TJPs, with the increase of zonulin-1 and 2, occluding and claudin-1, and to prevent inflammatory damage, in an in vitro model of intestinal barrier developed using Caco-2 cell monolayer [14]

If irritation persists or worsens, discontinue use and consult with your healthcare provider

Never freeze reconstituted solution as this destroys the peptide structure