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guidance from healthcare professionals improves safety and ensures injections target appropriate muscle or subcutaneous tissue
This work remains early-stage and confined to animal and in-vitro studies
Why it's included Included for its role in supporting fat metabolism and energy production
It is therefore clear that currently available GLP-1RAs, mimicking on the peripheral action of GLP-1 (7-36) NH2 , not only ignore the yet unknown physiology of GLP-1 (9-36) NH2 or its metabolites, but they also fail to address the tissue specific physiology of GLP-1 (7-36) NH2 , while pushing to supra-physiological limits the endocrine GLP-1 receptor axis, likely explaining the reported side-effects and only partial success in the treatment of T2D
Perez-Torres, I., Guarner-Lans, V
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