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TmMYB39 can interact with TmbHLH13 to form a TmMYB39-TmbHLH13 complex in Taxus madia , and significantly activate the expression of taxol biosynthesis genes GGPPS and T46OH , promoting the synthesis of taxol in Taxus media (Yu et al., 2022)
The Phase 2 trial showed 22.8% average body weight reduction at 48 weeks in the 8mg group
however, it is highly recommended to conduct a patch test prior to regular application of skincare products
These same anti-aging properties were also observed by a team from the NIA (National Institute of Aging) in mice[3, 5]: the increase in mouse life span ranged between 4.15% and 5.83% depending on the lines (while an overdose of metformin led to a reduction in life expectancy of 14.4%)[3, 5]
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