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Moreover, a phase 1 study has shown that retatrutide may decrease appetite and increase sensation of fullness and satiety in patients with type 2 diabetes [2]

Twice-daily exenatide (Byetta) requires more specific timing: it should be administered within 60 minutes before the two main meals of the day (typically breakfast and dinner), at least 6 hours apart

Interactions Interactions with other medicines Taking oral medications with a narrow therapeutic index, such as warfarin or digoxin, may be affected by tirzepatide, as it can alter their absorption

However, emerging studies reveal an additional benefitreducing the risk of heart disease