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Based on limited human pharmacology data, ipamorelin appears relatively selective, with less pronounced effects on cortisol and prolactin secretion compared with some other GH secretagogues though this selectivity has not been extensively validated in large human trials
These data are also consistent with patients in which DPP4 inhibitors (DPP4is) decrease HGP and are associated with reductions in glucagon (26, 34)
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So I hate to beat a dead horse, but like when a primary care has six minutes on average with a patient and they're limited in what tests they can do and what diagnostic tools they can run, and a woman comes in and says, hey, I'm 40 pounds overweight, I'm depressed, I'm anxious, I'm sad, I'm all these things, their first move is to go, okay, well, we got to get your cholesterol under control, we got to get your insulin under control
They recognize that clinical trials showed modest effects (average 2.6 kg over 12 weeks in responders), appreciate that individual response varies significantly, commit to proper nutrition and exercise foundations, and accept that the peptide is used for research purposes under medical supervision
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