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Beyond their primary metabolic effects, emerging evidence suggests cardiovascular benefits , including potential blood pressure reduction

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This Review addresses the effects of bariatric surgery on glucose regulation and the potential mechanisms responsible for both the resolution of T2DM and the induction of hypoglycaemia

It is believed that imbalanced gut microflora may contribute to CKD progression, but CKD also appears to disrupt the intestinal environment and affect microbiome composition

Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, and diarrhea, which typically diminish with continued use