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While anatomic narrowing of the upper airway is a critical factor, most patients also exhibit abnormalities in nonanatomic traits, such as pharyngeal muscle responsiveness, central neurohormonal control of breathing, and an awakening response [10]
Diabetes 66(2):235240 Vega RB, Whytock KL, Gassenhuber J, Goebel B, Tillner J, Agueusop I et al (2021) A metabolomic signature of glucagon action in healthy individuals with overweight/obesity
Preliminary pharmacogenomic studies suggest that polymorphisms in GLP-1 receptor genes could influence both efficacy and tolerability, but clinical genetic testing is not currently recommended for routine practice
ZP-6590 in combination with semaglutide produced mean weight losses of around 25% after 34 days in mice
