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These therapies display higher efficiency compared to classical senolytic drugs (BCL-2 or tyrosine kinase inhibitors) but for some of them, such as NA + /K + ATPase inhibitors, clinical development could be complex in the light of strong cardiotoxicity associated with this class of molecules

Mechanistically: catalase mRNA +1.7-fold, SOD1 mRNA +1.4-fold, GPx1 mRNA +1.6-fold (RT-qPCR

This bacteriostatic (growth-inhibiting) property, rather than a bactericidal (bacteria-killing) effect, ensures that any contaminating microbes do not multiply

Each batch is produced to rigorous quality standards and is accompanied by comprehensive testing documentation to help researchers verify product specifications

This triggers a massive demand for ATP to restore homeostasis just as cerebral blood flow is often restricted