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And any product calling itself natural fruit-flavored or honey-infused deserves an eyebrow raise

Rybelsus carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)

It commonly involves prior authorization, limiting coverage to Food and Drug Administration-approved uses (type 2 diabetes and obesity, in the case of GLP-1s) and requiring proof of progress (i.e., ongoing weight loss) for continued coverage

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Insulin users wanting to reduce doses: GLP-1 medications often allow substantial insulin reduction while improving control