It refers to gradually increasing the dose of GLP-1 medications to improve effectiveness while minimizing side effects
Others find the drugs dont work as well as before
Biomarkers and Baseline Health Screening Before Starting GLP-1 Evaluating baseline GI healthincluding stool consistency patterns, inflammatory markers (CRP, fecal calprotectin), and gastric motility historycan inform provider expectations for adaptation timing
Mari G, Gazibara T, Zaletel I, Labudovi Borovi M, Tomanovi N, iri M, et al
Large meals, fatty foods, caffeine, alcohol, and spicy or acidic foods are the most common triggers that worsen acid reflux in GLP-1s