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Dong L-H, Li L, Song Y, Duan Z-L, Sun S-G, Lin Y-L, et al
Definition Box Signal Peptide: A short peptide sequence that triggers downstream cellular responses (gene expression, enzyme activation, cytokine release) by interacting with receptors or transport proteins rather than by being incorporated into larger structures
Challenges in Medication Adherence While the study couldnt pinpoint the precise reasons behind patients halting their medication usage, researchers hypothesized that the gastrointestinal side effects significantly influenced these decisions
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What is already known on this topic Concerns exist about a potential association between glucagon-like peptide-1 receptor (GLP-1) agonists and suicidality This has prompted regulatory agencies to conduct comprehensive reviews of this drug class Observational studies investigating this safety concern remain inconclusive
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