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Exercise remains a cornerstone of obesity management, and combined exercise with GLP-1RA therapy can support weight maintenance [49]
The ventral tegmental area (VTA) and nucleus accumbens (NAc), key brain areas involved in the reinforcing effects of food and alcohol abuse, contain GLP-1 receptors, indicating central mediation of GLP-1 agonists 10
GLP-1 agonists promote satiety, delay gastric emptying and reduce hunger signals, making it easier to maintain a caloric deficit
Hydration tracking effectively monitors water intake, while macro tracking helps users meet their protein targets, even when eating feels difficult
Epigenetic modifications, such as histone acetylation and lactylation, have emerged as vital regulators of tubular necroptosis
