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Compared to HRP, APEX lacks disulfide and calcium-binding sites, has a smaller molecular weight (approximately 28 kD), and functions as a monomer
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The package contains a lot-specific Certificate of Analysis covering HPLC purity, LC-MS identity, and the LAL endotoxin reading, along with a Safety Data Sheet and a brief handling reference
Approval requires large controlled human trials
Recruited originally to help improve laundry detergent enzymes to make clothes look brighter, Knudsen soon got drawn into a small team set up in 1990 by Ole Kirk, an organic chemist and physician, to discover new peptide candidates to treat type 2 diabetes (Molteni, Chen
