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Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, et al

Although promising, most of the published studies have been in animal models rather than large-scale human clinical trials

While GHK-Cu is generally well-tolerated in topical research, certain contraindications or precautions should be considered, especially for systemic research or in specific populations: Systemic Research: For systemic applications, GHK-Cu is generally not recommended for subjects who are pregnant, breastfeeding, have active cancer, or suffer from Wilsons disease (a condition involving copper accumulation)

Warnings & Precautions: Black box warning: Risk of thyroid C-cell tumors observed in rodents

Remember, GLP-1 RAs were designed to treat type 2 diabetes