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In terms of genetics, ferroptosis leads to changes in iron transport pathways, RAS/MAPK/Raf pathways, and cysteine transport pathways, such as those including cyclooxygenase-2 (Cox2), ACSL4, and NADPH oxidases 1 (NOX1) genes, while also downregulating GPX4, solute carrier family 7 member 11 (SLC7A11), and Ferritin (30)
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