This process results in thyroidal gland damage and, depending on the degree of damage, usually leaves the patient hypothyroid and requiring thyroid hormone replacement
Additionally, proinflammatory cascades triggered by TECs promote the recruitment of leukocytes and dilation of the vasculature, affecting both the injured TECs and their surrounding microenvironment [12] (Fig
PPAR is also involved in carnitine transport and uptake processes, and treatment with its activator increases the transcript levels of OCTN2 and OCTN3 [195, 196]
Mechanistic insight provided by glutaredoxin within a fusion to redox-sensitive yellow fluorescent protein
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