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One thing to consider is that because ME/CFS is a severely disabling disease, many patients are house or bedbound and are unable to visit the clinics multiple times for follow-up analyses (587)
Ogata, M., Fryling, C
According to the SmPC and STEP clinical trials, these include: Nausea (affecting approximately 40-45% of patients) Vomiting (approximately 15-25% of patients) Diarrhoea (affecting approximately 25-30% of users) Constipation (approximately 20-25% of patients) Abdominal pain and bloating Gastro-oesophageal reflux For individuals taking oral anti-epileptic medications , severe or persistent vomiting could theoretically reduce drug absorption, potentially affecting seizure control
& Fraga, M
J Control Release 106:298308 Subedi L, Bamjan AD, Phuyal S, Shim J-H, Cho -S-S, Seo JB, Chang K-Y, Byun Y, Kweon S, Park JW (2025) An oral liraglutide nanomicelle formulation conferring reduced insulin-resistance and long-term hypoglycemic and lipid metabolic benefits
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