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The 3-year SURMOUNT-1 extension ( NEJM , 2024) found only 1.3% of Tirzepatide participants developed T2D versus 13.3% placebo a 93% relative risk reduction
Glucagon-like peptide-1 receptor agonists are similar to the GLP-1 hormone, which is secreted in the gastrointestinal tract in response to eating
J.BrooksA
Some patients describe previously enjoyed desserts, chocolate, or sugary beverages as less palatable or even unpleasant
Missing doses or irregular timing disrupts this accumulation
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