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This metabolic roadblock explains why patients with ME/CFS and Long COVID experience such profound, unyielding fatigue

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Figure 3 From Figure 3, a process labelled (1) shows the biosynthesis of GSH where GSH is synthesized from its constituent amino acids, cysteine, and glutamate, through a two-step ATP-dependent reaction catalyzed by the enzymes -ECS and GSHS

Abruptly stopping the medication often leads to weight regain, so a planned approach is preferable