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Physical activity programmes : Structured exercise interventions combining aerobic activity (150+ minutes weekly) and resistance training can enhance weight loss maintenance, preserve lean muscle mass, and improve metabolic health, as recommended by UK Chief Medical Officers' guidelines
It is worth mentioning that we also used univariable MR (UVMR) and multivariable MR (MVMR) analyses to identify the risk factors whose effects on MASLD were independent of BMI to figure out whether the causal effect of GLP-1R-based agonists on MASLD was fully dependent on their weight-loss effect
[7] [8] Additionally, GLP-1 signaling may influence GABAergic and glutamatergic neurotransmission, further modulating reward-related neural activity
Kowalchick JE, Leiting B, Pryor KD, Marsilio F, Wu JK, He H, et al
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